Cancer remains one of the deadliest diseases, with colorectal cancer emerging as a fast-growing concern worldwide. According to the World Health Organization (WHO), colorectal cancer is the third most common cancer globally and the second leading cause of cancer-related deaths. Modern lifestyle choices and unhealthy diets are fueling its rise.
The good news is, new research suggests that adequate levels of Vitamin D in the body can lower the risk of colorectal cancer by as much as 60%. Often called the “sunshine vitamin”, Vitamin D is naturally produced when the skin is exposed to sunlight and plays a vital role in many essential body functions.
A comprehensive WHO study published in April 2025 analyzed over 10,000 research papers, narrowing down to 50 key studies. The findings were clear: individuals with lower Vitamin D levels faced a significantly higher risk of developing colorectal cancer. A meta-analysis of 31 studies revealed that those with the highest Vitamin D levels had a 25% lower risk. Similarly, the famous Nurses’ Health Study found that women who consumed sufficient Vitamin D had up to a 58% reduced risk of colorectal cancer.
Experts highlight that Vitamin D doesn’t just support bone health—it also helps regulate cell growth and reduces inflammation, both of which are critical in preventing the uncontrolled cell division that leads to cancer.
Combination of Vitamin D, Omega-3, and Exercise
A separate study published in the Journal Frontiers in Aging showed even more promising results. Researchers found that in people aged 70 and above, a combination of Vitamin D supplements, Omega-3 fatty acids, and regular exercise reduced overall cancer risk by 61%.
The study followed 2,157 participants from Switzerland, France, Germany, Austria, and Portugal over three years. The results showed that while each factor alone offered some benefits, the combination of all three had the strongest impact in reducing the risk of invasive cancers.
The Role of Omega-3
Omega-3 fatty acids—commonly found in fish oil—are known for their anti-inflammatory properties. They help keep cells healthy and prevent them from turning cancerous. Scientists believe that Omega-3 works alongside Vitamin D and physical activity to provide a powerful protective shield against cancer.